منابع مشابه
Small but mighty: Platelets as central effectors of host defense.
Platelets actively participate in inflammatory processes and drive diseases such as atherosclerosis, rheumatoid arthritis and cancer metastasis. However, platelets also have anti-inflammatory and anti-infective properties, which have received less consideration in the past. In this review, we highlight recent findings on the role of platelets in host defense and describe regulatory pathways mod...
متن کاملMicroexons--tiny but mighty.
The landscape of alternative splicing is only beginning to unravel, and the functional consequences are often unclear. Two articles in Cell and Genome Research focus on a set of largely ignored yet highly conserved exons, microexons. These appear strongly regulated by RNA-binding proteins (RBPs) and functionally modulate protein–protein interactions with strong evidence for deregulation in auti...
متن کاملThe microRNA world: small is mighty.
A new paradigm of RNA-directed gene expression regulation has emerged recently, profound in scope but arresting in the apparent simplicity of its core mechanism. Cells express numerous small ( approximately 22 nucleotide) RNAs that act as specificity determinants to direct destruction or translational repression of their mRNA targets. These small RNAs arise from processing of double-stranded RN...
متن کاملSmall but Mighty: Affective Micropatterns for Quantifying Mental Health from Social Media Language
Many psychological phenomena occur in small time windows, measured in minutes or hours. However, most computational linguistic techniques look at data on the order of weeks, months, or years. We explore micropatterns in sequences of messages occurring over a short time window for their prevalence and power for quantifying psychological phenomena, specifically, patterns in affect. We examine aff...
متن کاملMighty small: Observing and modeling individual microbes becomes big science.
Jan-Ulrich Kreft, Caroline M. Plugge, Volker Grimm, Clara Prats, Johan H. J. Leveau, Thomas Banitz, Stephen Baines, James Clark, Alexandra Ros, Isaac Klapper, Chris J. Topping, Anthony J. Field, Andrew Schuler, Elena Litchman, and Ferdi L. Hellweger Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom; Laboratory of Microbiol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2000
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35040669